Planning ahead for my new layout.

I am not sure how big it will end up being since I have a big room but starting small and planning to add.

1) If I go with 22 AWG for feeder wires and 12 AWG for wire bus am I ok for a while?

2) What king of scotchlok connectors, or alike, that will fit my wire choice are you using?

3) Any other advice on wiring is welcome too.

Thanks

That will be more than adequate you will find, unless you have extremely heavy current loads.

In fact I would work on 16AWG for the bus wire, as being plenty heavy enough.

For bus wires: let the availability of the wire on rolls at your local building supply store determine the precise gauge you use for bus wires.
Copper wire is expensive and you probably need at least three colors. So look at what rolls bigger than 20 AWG are available in the overestimated length you need. You may find house wiring the most economical. 12AWG turnout to be most economical for me.

Similarly, look at the Skotchlock connecters that are available in bulk and buy wires that are within the range of sizes they can handle.

I use 3M Scotchlock Self-Stripping Electrical Tap Connectors 905

Then the hookup wires, again look at what you can get locally and also online. For every meter of K-track I lay, I use at least 50cm of brown, 25cm red and 25cm of some other color for s88 sensors.